Acute exercise leads to varying peptide YY levels in adults: A meta-analysis

BACKGROUND: Acute exercise is believed to regulate appetite and influence feeding behaviors by controlling the synthesis and secretion of gastrointestinal peptide hormones to regulate appetite and feeding behavior influence, but the small sample size leads to widely different results. OBJECTIVE: To clarify the effect of acute exercise on peptide YY levels in adults using Meta-analysis method. METHODS: A computer-based search of PubMed, Google Scholar, Sport Discus, Web of Knowledge and CNKI was performed for relevant articles published before January 2014. The literatures eligible were studied by evaluating the publication bias, checking the heterogeneity and analyzing the sensitivity by software of RevMan5.1. RESULTS AND CONCLUSION: (1) There were a total of 188 participants in the 18 trials reported in 11 articles. The Meta-analysis results revealed a mean effect for acute exercise to increase peptide YY values (standardized mean difference=0.25, 95% confidence interval =0.05-0.46, P=0.01), and therefore, there was a significantly statistical difference in the peptide YY levels between the acute exercise group and control group (P < 0.05). Moreover, results from the sensitivity analysis showed no influences on the findings of Meta-analysis. (2) Five randomized controlled trails in the three included articles were related to peptide YY (3-36). There was a maximal heterogeneity among these studies; therefore, a random-effect model was utilized. The result revealed a meaneffect for acute exercise to increase peptide YY (3-36) values (standardized mean difference =1.80, 95% confidence interval =0.27-3.32, P=0.02). The findings from this meta-analysis show that acute exercise may influence appetite by increasing levels of peptide YY in adults.