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Bifunctional CuS composite nanofibers via in situ electrospinning for outdoor rapid hemostasis and simultaneous ablating superbug

  • Xiao Fei Liu
  • , Jun Zhang
  • , Jiang Jun Liu
  • , Qi Hui Zhou
  • , Zhongqiang Liu
  • , Peng Yue Hu
  • , Zhe Yuan
  • , Seeram Ramakrishna
  • , Da Peng Yang
  • , Yun Ze Long
  • Qingdao University
  • Medical College of Qingdao University
  • National University of Singapore
  • Quanzhou Normal University

Research output: Contribution to journalArticlepeer-review

95 Scopus citations

Abstract

Outdoor sports or combat missions, such as jungle adventures or counter-piracy operations, often involve bleeding and infected wounds. Due to the poor and limited medical conditions in these outdoor situations, patients prefer an easy way to simultaneously treat blood loss and wound infection by using the same outdoor device and the same material. In this study, a portable electrospinning device (150 g in weight) for outdoor use was developed, and CuS composite nanofibers could be green-synthesized by this portable electrospinning device. These CuS composite nanofibers can be deposited in situ onto the wound to simultaneously achieve rapid hemostasis outdoors and ablate superbacteria without requiring the use of other materials or devices. These in situ electrospun nanofibers possess better compactness on the rough wound surface than conventional nanofiber mats pressed onto the wound site. Thus, the nanofiber not only accelerates the hemostasis (<6 s) but also shortens the healing time of the wound with superbacterial infection (18 days). These bifunctional nanofibers combined with a portable electrospinning device for outdoor rapid hemostasis and simultaneous superbug ablation could notably benefit the outdoor first aid.

Original languageEnglish
Article number126096
JournalChemical Engineering Journal
Volume401
DOIs
StatePublished - 1 Dec 2020
Externally publishedYes

Keywords

  • CuS composite nanofibers
  • Electrospinning
  • In situ hemostasis
  • Outdoor use
  • Superbacterial infection

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