Carboxymethylcellulose-based aggregation-induced emission antibacterial material for multifunctional applications

  • Jingfei Wang
  • , Meiyi Wu
  • , Ruiting Zhang
  • , Chongruihan Li
  • , Chaoqun Li
  • , Shuangling Zhong
  • , Yan Gao
  • , Qingye Meng
  • , Xuejun Cui

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Polysaccharides are ubiquitous in nature, typically harmless, and highly compatible with various tissues in biomedical contexts. These properties make them attractive for use in multifunctional materials. In this study, the aggregation-induced emission (AIE) antibacterial material (PLOCMC) was successfully synthesized by carboxymethylcellulose (CMC) and ε-Poly-Lysine (ε-PL). PLOCMC exhibits not only the AIE property but also a room temperature phosphorescent (RTP) phenomenon. This dual emission behavior enhances its potential applications in chemical sensing and anti-counterfeiting. Notably, PLOCMC shows low cytotoxicity and exhibits antibacterial activity against typical Gram-positive and Gram-negative bacteria, making it a potent agent against a variety of bacterial strains. Additionally, PLOCMC demonstrates specific responsiveness to Fe3+ ions and nitrite, indicating its potential utility in food safety and monitoring applications.

Original languageEnglish
Article number137740
JournalInternational Journal of Biological Macromolecules
Volume283
DOIs
StatePublished - Dec 2024

Keywords

  • Aggregation-induced emission
  • Antibacterial agents
  • Carboxymethyl cellulose
  • Schiff-base
  • ε-Poly-lysine

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