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Comparison of non-negative matrix factorization methods for clustering genomic data

  • Mi Xiao Hou
  • , Ying Lian Gao
  • , Jin Xing Liu
  • , Jun Liang Shang
  • , Chun Hou Zheng
  • Qufu Normal University
  • Harbin Institute of Technology

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

3 Scopus citations

Abstract

Non-negative matrix factorization (NMF) is a useful method of data dimensionality reduction and has been widely used in many fields, such as pattern recognition and data mining. Compared with other traditional methods, it has unique advantages. And more and more improved NMF methods have been provided in recent years and all of these methods have merits and demerits when used in different applications. Clustering based on NMF methods is a common way to reflect the properties of methods. While there are no special comparisons of clustering experiments based on NMF methods on genomic data. In this paper, we analyze the characteristics of basic NMF and its classical variant methods. Moreover, we show the clustering results based on the coefficient matrix decomposed by NMF methods on the genomic datasets. We also compare the clustering accuracies and the cost of time of these methods.

Original languageEnglish
Title of host publicationIntelligent Computing Theories and Application - 12th International Conference, ICIC 2016, Proceedings
EditorsDe-Shuang Huang, Kang-Hyun Jo
PublisherSpringer Verlag
Pages290-299
Number of pages10
ISBN (Print)9783319422930
DOIs
StatePublished - 2016
Externally publishedYes
Event12th International Conference on Intelligent Computing Theories and Application, ICIC 2016 - Lanzhou, China
Duration: 2 Aug 20165 Aug 2016

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume9772
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference12th International Conference on Intelligent Computing Theories and Application, ICIC 2016
Country/TerritoryChina
CityLanzhou
Period2/08/165/08/16

Keywords

  • Clustering
  • Dimensionality reduction
  • Genomic data
  • Non-negative matrix factorization

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