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Correntropy induced loss based sparse robust graph regularized extreme learning machine for cancer classification

  • Liang Rui Ren
  • , Ying Lian Gao
  • , Jin Xing Liu
  • , Junliang Shang
  • , Chun Hou Zheng
  • Qufu Normal University
  • Anhui University

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Background: As a machine learning method with high performance and excellent generalization ability, extreme learning machine (ELM) is gaining popularity in various studies. Various ELM-based methods for different fields have been proposed. However, the robustness to noise and outliers is always the main problem affecting the performance of ELM. Results: In this paper, an integrated method named correntropy induced loss based sparse robust graph regularized extreme learning machine (CSRGELM) is proposed. The introduction of correntropy induced loss improves the robustness of ELM and weakens the negative effects of noise and outliers. By using the L 2,1-norm to constrain the output weight matrix, we tend to obtain a sparse output weight matrix to construct a simpler single hidden layer feedforward neural network model. By introducing the graph regularization to preserve the local structural information of the data, the classification performance of the new method is further improved. Besides, we design an iterative optimization method based on the idea of half quadratic optimization to solve the non-convex problem of CSRGELM. Conclusions: The classification results on the benchmark dataset show that CSRGELM can obtain better classification results compared with other methods. More importantly, we also apply the new method to the classification problems of cancer samples and get a good classification effect.

Original languageEnglish
Article number445
JournalBMC Bioinformatics
Volume21
Issue number1
DOIs
StatePublished - 7 Oct 2020
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Bioinformatics
  • Correntropy induced loss
  • Extreme learning machine
  • Supervised learning

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