TY - GEN
T1 - Lasso logistic regression based approach for extracting plants coregenes responding to abiotic stresses
AU - Liu, Jinxing
AU - Zheng, Chunhou
AU - Xu, Yong
PY - 2011
Y1 - 2011
N2 - Sparse methods have a significant advantage of reducing gene expression data complexity to make them comprehensible and interpretable. In this paper, based on Lasso Logistic Regression (LLR), we propose a novel approach to extract plant characteristic gene set, namely coregenes, responding to abiotic stresses. Firstly, to obtain the regression coefficients, the lasso logistic regression was performed according to the samples. Then, the regression coefficients were sorted by the absolute value of them. Finally, the corresponding genes of the nonzero entries of the coefficients are selected as the coregene. Each of coregene extracted can capture the changes of the samples belong to the same condition. The experimental results show that the proposed LLR-based method is efficient to extract the coregenes concerning straight with the stresses.
AB - Sparse methods have a significant advantage of reducing gene expression data complexity to make them comprehensible and interpretable. In this paper, based on Lasso Logistic Regression (LLR), we propose a novel approach to extract plant characteristic gene set, namely coregenes, responding to abiotic stresses. Firstly, to obtain the regression coefficients, the lasso logistic regression was performed according to the samples. Then, the regression coefficients were sorted by the absolute value of them. Finally, the corresponding genes of the nonzero entries of the coefficients are selected as the coregene. Each of coregene extracted can capture the changes of the samples belong to the same condition. The experimental results show that the proposed LLR-based method is efficient to extract the coregenes concerning straight with the stresses.
UR - https://www.scopus.com/pages/publications/84863386440
U2 - 10.1109/IWACI.2011.6160051
DO - 10.1109/IWACI.2011.6160051
M3 - 会议稿件
AN - SCOPUS:84863386440
SN - 9781612843735
T3 - Proceedings of 4th International Workshop on Advanced Computational Intelligence, IWACI 2011
SP - 461
EP - 464
BT - Proceedings of 4th International Workshop on Advanced Computational Intelligence, IWACI 2011
T2 - 4th International Workshop on Advanced Computational Intelligence, IWACI 2011
Y2 - 19 October 2011 through 21 October 2011
ER -