Mitochondrial dysfunction in obesity-associated nonalcoholic fatty liver disease: The protective effects of pomegranate with its active component punicalagin

Xuan Zou; Chunhong Yan; Yujie Shi; Ke Cao; Jie Xu; Xun Wang; Cong Chen; Cheng Luo; Yuan Li; Jing Gao; Wentao Pang; Jialong Zhao; Fei Zhao; Hao Li; Adi Zheng; Wenyan Sun; Jiangang Long; Ignatius Man Yau Szeto; Youyou Zhao; Zhizhong Dong; Peifang Zhang; Junkuan Wang; Wuyuan Lu; Yong Zhang; Jiankang Liu; Zhihui Feng

doi:10.1089/ars.2013.5538

Mitochondrial dysfunction in obesity-associated nonalcoholic fatty liver disease: The protective effects of pomegranate with its active component punicalagin

Xuan Zou
, Chunhong Yan
, Yujie Shi
, Ke Cao
, Jie Xu
, Xun Wang
, Cong Chen
, Cheng Luo
, Yuan Li
, Jing Gao
, Wentao Pang
, Jialong Zhao
, Fei Zhao
, Hao Li
, Adi Zheng
, Wenyan Sun
, Jiangang Long
, Ignatius Man Yau Szeto
, Youyou Zhao
, Zhizhong Dong

Peifang Zhang, Junkuan Wang, Wuyuan Lu, Yong Zhang, Jiankang Liu, Zhihui Feng

Xi'an Jiaotong University
Nestle
Tianjin University of Sport

Research output: Contribution to journal › Article › peer-review

125 Scopus citations

Abstract

Aims: Punicalagin (PU) is one of the major ellagitannins found in the pomegranate (Punica granatum), which is a popular fruit with several health benefits. So far, no studies have evaluated the effects of PU on nonalcoholic fatty liver disease (NAFLD). Our work aims at studying the effect of PU-enriched pomegranate extract (PE) on high fat diet (HFD)-induced NAFLD.

Original language	English
Pages (from-to)	1557-1570
Number of pages	14
Journal	Antioxidants and Redox Signaling
Volume	21
Issue number	11
DOIs	https://doi.org/10.1089/ars.2013.5538
State	Published - 10 Oct 2014
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1089/ars.2013.5538

Cite this

Zou, X., Yan, C., Shi, Y., Cao, K., Xu, J., Wang, X., Chen, C., Luo, C., Li, Y., Gao, J., Pang, W., Zhao, J., Zhao, F., Li, H., Zheng, A., Sun, W., Long, J., Szeto, I. M. Y., Zhao, Y., ... Feng, Z. (2014). Mitochondrial dysfunction in obesity-associated nonalcoholic fatty liver disease: The protective effects of pomegranate with its active component punicalagin. Antioxidants and Redox Signaling, 21(11), 1557-1570. https://doi.org/10.1089/ars.2013.5538

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title = "Mitochondrial dysfunction in obesity-associated nonalcoholic fatty liver disease: The protective effects of pomegranate with its active component punicalagin",

abstract = "Aims: Punicalagin (PU) is one of the major ellagitannins found in the pomegranate (Punica granatum), which is a popular fruit with several health benefits. So far, no studies have evaluated the effects of PU on nonalcoholic fatty liver disease (NAFLD). Our work aims at studying the effect of PU-enriched pomegranate extract (PE) on high fat diet (HFD)-induced NAFLD.",

author = "Xuan Zou and Chunhong Yan and Yujie Shi and Ke Cao and Jie Xu and Xun Wang and Cong Chen and Cheng Luo and Yuan Li and Jing Gao and Wentao Pang and Jialong Zhao and Fei Zhao and Hao Li and Adi Zheng and Wenyan Sun and Jiangang Long and Szeto, \{Ignatius Man Yau\} and Youyou Zhao and Zhizhong Dong and Peifang Zhang and Junkuan Wang and Wuyuan Lu and Yong Zhang and Jiankang Liu and Zhihui Feng",

note = "Publisher Copyright: {\textcopyright} Mary Ann Liebert, Inc.",

year = "2014",

month = oct,

day = "10",

doi = "10.1089/ars.2013.5538",

language = "英语",

volume = "21",

pages = "1557--1570",

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Zou, X, Yan, C, Shi, Y, Cao, K, Xu, J, Wang, X, Chen, C, Luo, C, Li, Y, Gao, J, Pang, W, Zhao, J, Zhao, F, Li, H, Zheng, A, Sun, W, Long, J, Szeto, IMY, Zhao, Y, Dong, Z, Zhang, P, Wang, J, Lu, W, Zhang, Y, Liu, J & Feng, Z 2014, 'Mitochondrial dysfunction in obesity-associated nonalcoholic fatty liver disease: The protective effects of pomegranate with its active component punicalagin', Antioxidants and Redox Signaling, vol. 21, no. 11, pp. 1557-1570. https://doi.org/10.1089/ars.2013.5538

TY - JOUR

T1 - Mitochondrial dysfunction in obesity-associated nonalcoholic fatty liver disease

T2 - The protective effects of pomegranate with its active component punicalagin

AU - Zou, Xuan

AU - Yan, Chunhong

AU - Shi, Yujie

AU - Cao, Ke

AU - Xu, Jie

AU - Wang, Xun

AU - Chen, Cong

AU - Luo, Cheng

AU - Li, Yuan

AU - Gao, Jing

AU - Pang, Wentao

AU - Zhao, Jialong

AU - Zhao, Fei

AU - Li, Hao

AU - Zheng, Adi

AU - Sun, Wenyan

AU - Long, Jiangang

AU - Szeto, Ignatius Man Yau

AU - Zhao, Youyou

AU - Dong, Zhizhong

AU - Zhang, Peifang

AU - Wang, Junkuan

AU - Lu, Wuyuan

AU - Zhang, Yong

AU - Liu, Jiankang

AU - Feng, Zhihui

PY - 2014/10/10

Y1 - 2014/10/10

N2 - Aims: Punicalagin (PU) is one of the major ellagitannins found in the pomegranate (Punica granatum), which is a popular fruit with several health benefits. So far, no studies have evaluated the effects of PU on nonalcoholic fatty liver disease (NAFLD). Our work aims at studying the effect of PU-enriched pomegranate extract (PE) on high fat diet (HFD)-induced NAFLD.

AB - Aims: Punicalagin (PU) is one of the major ellagitannins found in the pomegranate (Punica granatum), which is a popular fruit with several health benefits. So far, no studies have evaluated the effects of PU on nonalcoholic fatty liver disease (NAFLD). Our work aims at studying the effect of PU-enriched pomegranate extract (PE) on high fat diet (HFD)-induced NAFLD.

UR - https://www.scopus.com/pages/publications/84905704899

U2 - 10.1089/ars.2013.5538

DO - 10.1089/ars.2013.5538

M3 - 文章

C2 - 24393106

AN - SCOPUS:84905704899

SN - 1523-0864

VL - 21

SP - 1557

EP - 1570

JO - Antioxidants and Redox Signaling

JF - Antioxidants and Redox Signaling

IS - 11

ER -

Mitochondrial dysfunction in obesity-associated nonalcoholic fatty liver disease: The protective effects of pomegranate with its active component punicalagin

Abstract

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