Review on design strategies and considerations of polysaccharide-based smart drug delivery systems for cancer therapy

Qingye Meng; Shuangling Zhong; Lifeng Xu; Jingfei Wang; Zhenqian Zhang; Yan Gao; Xuejun Cui

doi:10.1016/j.carbpol.2021.119013

Review on design strategies and considerations of polysaccharide-based smart drug delivery systems for cancer therapy

Qingye Meng
, Shuangling Zhong
, Lifeng Xu
, Jingfei Wang
, Zhenqian Zhang
, Yan Gao
, Xuejun Cui

Jilin University
Jilin Agricultural University
Jilin University

Research output: Contribution to journal › Review article › peer-review

96 Scopus citations

Abstract

The unique natural advantages of polysaccharide materials have attracted attention in biomedical applications. The abundant modifiable functional groups on the polysaccharide materials surface can facilitate the synthesis of various multifunctional drug delivery carriers. Especially in tumor therapy, the designs of polysaccharide-based drug delivery carriers are diverse. Therefore, this review summarized several latest types of polysaccharide-based drug carriers designs, and focused on the latest design strategies and considerations of drug carriers with polysaccharides as the main structure. It is expected to provide some design ideas and inspiration for subsequent polysaccharide-based drug delivery systems.

Original language	English
Article number	119013
Journal	Carbohydrate Polymers
Volume	279
DOIs	https://doi.org/10.1016/j.carbpol.2021.119013
State	Published - 1 Mar 2022
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cancer therapy
Drug delivery system
Polysaccharide

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10.1016/j.carbpol.2021.119013

Cite this

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title = "Review on design strategies and considerations of polysaccharide-based smart drug delivery systems for cancer therapy",

abstract = "The unique natural advantages of polysaccharide materials have attracted attention in biomedical applications. The abundant modifiable functional groups on the polysaccharide materials surface can facilitate the synthesis of various multifunctional drug delivery carriers. Especially in tumor therapy, the designs of polysaccharide-based drug delivery carriers are diverse. Therefore, this review summarized several latest types of polysaccharide-based drug carriers designs, and focused on the latest design strategies and considerations of drug carriers with polysaccharides as the main structure. It is expected to provide some design ideas and inspiration for subsequent polysaccharide-based drug delivery systems.",

keywords = "Cancer therapy, Drug delivery system, Polysaccharide",

author = "Qingye Meng and Shuangling Zhong and Lifeng Xu and Jingfei Wang and Zhenqian Zhang and Yan Gao and Xuejun Cui",

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doi = "10.1016/j.carbpol.2021.119013",

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T1 - Review on design strategies and considerations of polysaccharide-based smart drug delivery systems for cancer therapy

AU - Meng, Qingye

AU - Zhong, Shuangling

AU - Xu, Lifeng

AU - Wang, Jingfei

AU - Zhang, Zhenqian

AU - Gao, Yan

AU - Cui, Xuejun

PY - 2022/3/1

Y1 - 2022/3/1

N2 - The unique natural advantages of polysaccharide materials have attracted attention in biomedical applications. The abundant modifiable functional groups on the polysaccharide materials surface can facilitate the synthesis of various multifunctional drug delivery carriers. Especially in tumor therapy, the designs of polysaccharide-based drug delivery carriers are diverse. Therefore, this review summarized several latest types of polysaccharide-based drug carriers designs, and focused on the latest design strategies and considerations of drug carriers with polysaccharides as the main structure. It is expected to provide some design ideas and inspiration for subsequent polysaccharide-based drug delivery systems.

AB - The unique natural advantages of polysaccharide materials have attracted attention in biomedical applications. The abundant modifiable functional groups on the polysaccharide materials surface can facilitate the synthesis of various multifunctional drug delivery carriers. Especially in tumor therapy, the designs of polysaccharide-based drug delivery carriers are diverse. Therefore, this review summarized several latest types of polysaccharide-based drug carriers designs, and focused on the latest design strategies and considerations of drug carriers with polysaccharides as the main structure. It is expected to provide some design ideas and inspiration for subsequent polysaccharide-based drug delivery systems.

KW - Cancer therapy

KW - Drug delivery system

KW - Polysaccharide

UR - https://www.scopus.com/pages/publications/85121420633

U2 - 10.1016/j.carbpol.2021.119013

DO - 10.1016/j.carbpol.2021.119013

M3 - 文献综述

C2 - 34980356

AN - SCOPUS:85121420633

SN - 0144-8617

VL - 279

JO - Carbohydrate Polymers

JF - Carbohydrate Polymers

M1 - 119013

ER -

Review on design strategies and considerations of polysaccharide-based smart drug delivery systems for cancer therapy

Abstract

UN SDGs

Keywords

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