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Sparse Regularization Tensor Robust PCA Based on t-product and Its Application in Cancer Genomic Data

  • Hang Jin Yang
  • , Yu Ying Zhao
  • , Jin Xing Liu
  • , Yu Xia Lei
  • , Jun Liang Shang
  • , Xiang Zhen Kong
  • Qufu Normal University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

7 Scopus citations

Abstract

Genetic information becomes more and more important in the process of biological research. Gene analysis is an effective mean in biological research, especially the analysis of differentially expressed genes. Robust principal component analysis (RPCA) is an effective method to identify differentially expressed genes. But tensor robust principal component analysis (TRPCA) performs better than RPCA when processing multi-dimensional data. The traditional TRPCA method also has limitations in restoring low-rank sparse components. To further improve the accuracy of the TRPCA method in restoring low-rank components and sparse components, we propose a novel TRPCA method to obtain high-order correlations information of multi-dimensional data. It uses a new nuclear norm based on t-product operator to approximate the rank function. The L_{2,1} -norm is used to improve the sparsity of tensors and reduce the negative effects caused by noises and outliers. At the same time, the introduction of L_{2,1} -norm enhances the sparsity of error components, and improves the accuracy of low-rank component recovery. The low-rank sparse components are obtained by solving the convex problem of the new tensor nuclear norm. It can well preserve the spatial structure and make full use of complementary information to improve the clustering effect. Alternating direction method of multiplier (ADMM) is used to solve the optimization problem of this method. Experimental results on different cancer genomic datasets indicate that our method is superior to other methods.

Original languageEnglish
Title of host publicationProceedings - 2020 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2020
EditorsTaesung Park, Young-Rae Cho, Xiaohua Tony Hu, Illhoi Yoo, Hyun Goo Woo, Jianxin Wang, Julio Facelli, Seungyoon Nam, Mingon Kang
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages2131-2138
Number of pages8
ISBN (Electronic)9781728162157
DOIs
StatePublished - 16 Dec 2020
Externally publishedYes
Event2020 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2020 - Virtual, Seoul, Korea, Republic of
Duration: 16 Dec 202019 Dec 2020

Publication series

NameProceedings - 2020 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2020

Conference

Conference2020 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2020
Country/TerritoryKorea, Republic of
CityVirtual, Seoul
Period16/12/2019/12/20

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • average rank
  • clustering
  • sparse
  • t-product
  • tensor nuclear norm

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