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A compressed sensing based feature extraction method for identifying characteristic genes

  • Qufu Normal University

科研成果: 书/报告/会议事项章节会议稿件同行评审

摘要

In current molecular biology, it becomes more and more important to identify characteristic genes closely correlated with a key biological process from gene expression data. In this paper, a novel compressed sensing (CS) based feature extraction method named CSGS is proposed to identify the characteristic genes. Considering the transposed gene expression matrix and class labels as sensing matrix and measurement vector, respectively, CS reconstruction is implemented by basis pursuit algorithm. Top ranking genes with high signal weights are retained as the characteristic genes. Experiments of CSGS are performed on leukemia data set and compared with other sparse methods. Results demonstrate that CSGS is effective in identifying characteristic genes, and is not sensitive to parameters. CSGS could offer a simple way for feature extraction and provide more clues for biologists.

源语言英语
主期刊名Intelligent Computing Theories and Application - 12th International Conference, ICIC 2016, Proceedings
编辑De-Shuang Huang, Kang-Hyun Jo
出版商Springer Verlag
67-77
页数11
ISBN(印刷版)9783319422930
DOI
出版状态已出版 - 2016
已对外发布
活动12th International Conference on Intelligent Computing Theories and Application, ICIC 2016 - Lanzhou, 中国
期限: 2 8月 20165 8月 2016

出版系列

姓名Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
9772
ISSN(印刷版)0302-9743
ISSN(电子版)1611-3349

会议

会议12th International Conference on Intelligent Computing Theories and Application, ICIC 2016
国家/地区中国
Lanzhou
时期2/08/165/08/16

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