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An improved particle swarm optimization with dynamic scale-free network for detecting multi-omics features

  • Huiyu Li
  • , Sheng Jun Li
  • , Junliang Shang
  • , Jin Xing Liu
  • , Chun Hou Zheng
  • Qufu Normal University
  • Anhui University

科研成果: 书/报告/会议事项章节会议稿件同行评审

1 引用 (Scopus)

摘要

Along with the rapid development of high-throughput sequencing technology, a large amount of multi-omics data sets are generated, which provide more opportunities to understand the mechanism of complex diseases. In this study, an improved particle swarm optimization with dynamic scale-free network, named DSFPSO, is proposed for detecting multi-omics features. The highlights of DSFPSO are the introduced scale-free network and velocity updating strategies. The scale-free network is employed to DSFPSO as its population structure, which can dynamically adjust the iteration processes. Three types of velocity updating strategies are used in DSFPSO for fully considering the heterogeneity of particles and their neighbors. Both gene function analysis and pathway analysis on colorectal cancer (CRC) data show that DSFPSO can detect CRC-associated features effectively.

源语言英语
主期刊名Bioinformatics Research and Applications - 14th International Symposium, ISBRA 2018, Proceedings
编辑Fa Zhang, Shihua Zhang, Zhipeng Cai, Pavel Skums
出版商Springer Verlag
26-37
页数12
ISBN(印刷版)9783319949673
DOI
出版状态已出版 - 2018
已对外发布
活动14th International Symposium on Bioinformatics Research and Applications, ISBRA 2018 - Beijing, 中国
期限: 8 6月 201811 6月 2018

出版系列

姓名Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
10847 LNBI
ISSN(印刷版)0302-9743
ISSN(电子版)1611-3349

会议

会议14th International Symposium on Bioinformatics Research and Applications, ISBRA 2018
国家/地区中国
Beijing
时期8/06/1811/06/18

联合国可持续发展目标

此成果有助于实现下列可持续发展目标:

  1. 可持续发展目标 3 - 良好健康与福祉
    可持续发展目标 3 良好健康与福祉

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