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Identifying characteristic genes based on robust principal component analysis

  • Anhui University
  • Harbin Institute of Technology
  • Qufu Normal University

科研成果: 书/报告/会议事项章节会议稿件同行评审

2 引用 (Scopus)

摘要

In this paper, based on robust PCA, a novel method of characteristic genes identification is proposed. In our method, the differentially expressed genes and non-differentially expressed genes are treated as perturbation signals S 0 and low-rank matrix A 0, respectively, which can be recovered from the gene expression data using robust PCA. The scheme to identify the characteristic genes is as following. Firstly, the matrix S 0 of perturbation signals is discovered from gene expression data matrix D by using robust PCA. Secondly, the characteristic genes are selected according to matrix S 0. Finally, the characteristic genes are checked by the tool of Gene Ontology. The experimental results show that our method is efficient and effective.

源语言英语
主期刊名Emerging Intelligent Computing Technology and Applications - 8th International Conference, ICIC 2012, Proceedings
174-179
页数6
DOI
出版状态已出版 - 2012
已对外发布
活动8th International Conference on Emerging Intelligent Computing Technology and Applications, ICIC 2012 - Huangshan, 中国
期限: 25 7月 201229 7月 2012

出版系列

姓名Communications in Computer and Information Science
304 CCIS
ISSN(印刷版)1865-0929

会议

会议8th International Conference on Emerging Intelligent Computing Technology and Applications, ICIC 2012
国家/地区中国
Huangshan
时期25/07/1229/07/12

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