Linkage analysis of X-linked nuclear protein gene in Smith-Fineman-Myers syndrome

Qiji Liu; Yaoqin Gong; Bingxi Chen; Chenhong Guo; Jiangxia Li; Yishou Guo

Linkage analysis of X-linked nuclear protein gene in Smith-Fineman-Myers syndrome

Qiji Liu
, Yaoqin Gong
, Bingxi Chen
, Chenhong Guo
, Jiangxia Li
, Yishou Guo

Shandong University

科研成果: 期刊稿件 › 文章 › 同行评审

4 引用（Scopus）

摘要

Objective To determine the linkage between Smith-Fineman-Myers syndrome (SFMS) and X-linked nuclear protein (XNP) locus. Methods Polymerase chain reaction and denaturing polyacrylamide gel electrophoresis were used to genotype two polymorphic short tandem repeats within XNP gene. Results One of the two short tandem repeats was informative in SFMS family from Shandong, China. Recombination between SFMS locus and XNP gene was observed in the SFMS family. Conclusion XNP gene is not associated with the disease in the SFMS family from Shandong, China. SFMS exhibits locus heterogeneity at molecular level.

源语言	英语
页（从-至）	22-25
页数	4
期刊	Chinese Journal of Medical Genetics
卷	19
期	1
出版状态	已出版 - 2002
已对外发布	是

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title = "Linkage analysis of X-linked nuclear protein gene in Smith-Fineman-Myers syndrome",

abstract = "Objective To determine the linkage between Smith-Fineman-Myers syndrome (SFMS) and X-linked nuclear protein (XNP) locus. Methods Polymerase chain reaction and denaturing polyacrylamide gel electrophoresis were used to genotype two polymorphic short tandem repeats within XNP gene. Results One of the two short tandem repeats was informative in SFMS family from Shandong, China. Recombination between SFMS locus and XNP gene was observed in the SFMS family. Conclusion XNP gene is not associated with the disease in the SFMS family from Shandong, China. SFMS exhibits locus heterogeneity at molecular level.",

keywords = "Linkage analysis, Smith-Fineman-Myers syndrome, X-linked nuclear protein gene",

author = "Qiji Liu and Yaoqin Gong and Bingxi Chen and Chenhong Guo and Jiangxia Li and Yishou Guo",

year = "2002",

language = "英语",

volume = "19",

pages = "22--25",

journal = "Chinese Journal of Medical Genetics",

issn = "1003-9406",

publisher = "Chinese Medical Journals Publishing House Co.Ltd",

number = "1",

}

TY - JOUR

T1 - Linkage analysis of X-linked nuclear protein gene in Smith-Fineman-Myers syndrome

AU - Liu, Qiji

AU - Gong, Yaoqin

AU - Chen, Bingxi

AU - Guo, Chenhong

AU - Li, Jiangxia

AU - Guo, Yishou

PY - 2002

Y1 - 2002

N2 - Objective To determine the linkage between Smith-Fineman-Myers syndrome (SFMS) and X-linked nuclear protein (XNP) locus. Methods Polymerase chain reaction and denaturing polyacrylamide gel electrophoresis were used to genotype two polymorphic short tandem repeats within XNP gene. Results One of the two short tandem repeats was informative in SFMS family from Shandong, China. Recombination between SFMS locus and XNP gene was observed in the SFMS family. Conclusion XNP gene is not associated with the disease in the SFMS family from Shandong, China. SFMS exhibits locus heterogeneity at molecular level.

AB - Objective To determine the linkage between Smith-Fineman-Myers syndrome (SFMS) and X-linked nuclear protein (XNP) locus. Methods Polymerase chain reaction and denaturing polyacrylamide gel electrophoresis were used to genotype two polymorphic short tandem repeats within XNP gene. Results One of the two short tandem repeats was informative in SFMS family from Shandong, China. Recombination between SFMS locus and XNP gene was observed in the SFMS family. Conclusion XNP gene is not associated with the disease in the SFMS family from Shandong, China. SFMS exhibits locus heterogeneity at molecular level.

KW - Linkage analysis

KW - Smith-Fineman-Myers syndrome

KW - X-linked nuclear protein gene

UR - https://www.scopus.com/pages/publications/0036181063

M3 - 文章

C2 - 11836680

AN - SCOPUS:0036181063

SN - 1003-9406

VL - 19

SP - 22

EP - 25

JO - Chinese Journal of Medical Genetics

JF - Chinese Journal of Medical Genetics

IS - 1

ER -

Linkage analysis of X-linked nuclear protein gene in Smith-Fineman-Myers syndrome

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