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Robust Graph Regularized Extreme Learning Machine Auto Encoder and Its Application to Single-Cell Samples Classification

  • Liang Rui Ren
  • , Jin Xing Liu
  • , Ying Lian Gao
  • , Xiang Zhen Kong
  • , Chun Hou Zheng
  • Qufu Normal University
  • Anhui University

科研成果: 书/报告/会议事项章节会议稿件同行评审

摘要

Combined with Auto Encoder (AE), Extreme Learning Machine Auto Encoder (ELM-AE) has attracted the interest of researchers in recent years. Considering the classification tasks of single-cell Ribonucleic Acid sequencing (scRNA-seq) data, in this paper, we propose a novel supervised learning method based on ELM-AE, which is named Robust Graph Regularized Extreme Learning Machine Auto Encoder (RGELMAE). The method introduces L2,1-norm minimization on loss function to improve the robustness, and combines with the manifold regularization framework to explore the internal local structure between data points. Finally, RGELMAE is applied to the classification tasks of scRNA-seq data. The experimental results indicate that our method can effectively extract the key information representing the original data, and improve the classification performance of ELM.

源语言英语
主期刊名Intelligent Computing Theories and Application - 16th International Conference, ICIC 2020, Proceedings
编辑De-Shuang Huang, Kang-Hyun Jo
出版商Springer Science and Business Media Deutschland GmbH
537-545
页数9
ISBN(印刷版)9783030608019
DOI
出版状态已出版 - 2020
已对外发布
活动16th International Conference on Intelligent Computing, ICIC 2020 - Bari , 意大利
期限: 2 10月 20205 10月 2020

出版系列

姓名Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
12464 LNCS
ISSN(印刷版)0302-9743
ISSN(电子版)1611-3349

会议

会议16th International Conference on Intelligent Computing, ICIC 2020
国家/地区意大利
Bari
时期2/10/205/10/20

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